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Insights on the impact of mitochondrial organisation on bioenergetics in high-resolution computational models of cardiac cell architecture

Fig 9

Spatial variation in rates of CK enzymatic reactions involved in phosphocreatine shuttle under normoxia and hypoxia.

All the figures were generated by using same colour spectrum range. (A): Steady state profiles of reaction rates of mitochondrial mtCK in forward direction (ATP + Cr → PCr + ADP) (B): Steady state profiles showing reaction rates of myofibrilar MCK in reverse direction (PCr + ADP → ATP + Cr).

Fig 9

doi: https://doi.org/10.1371/journal.pcbi.1006640.g009