Coevolving residues inform protein dynamics profiles and disease susceptibility of nSNVs
Fig 10
Comparison of theoretical B-factors.
Boxplots comparing the correlations of predicted B-factors by our Seq-GNM for (a) RaptorX and (b) EVcouplings with that of the structural GNM for all 139 structures using a constant threshold for EC contacts. The GNM analysis is conducted 8 times using a constant threshold (between 0.92 and 0.99) each time. The best average correlations are produced when the constant threshold value of 0.98 is used.