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Chain organization of human interphase chromosome determines the spatiotemporal dynamics of chromatin loci

Fig 2

Subdiffusive behavior of chromatin loci.

(A) Loci- and time-averaged MSD generated from a single time trajectory in a log-log plot (Inset displays the time-averaged MSD for individual loci, color-coded by a normalized monomer index i/N.). (B) Time-averaged MSD of the midpoint monomer , and the center of mass of the whole chain in a log-log plot. The horizontal dashed line labels the mean square end-to-end distance (= 62.7 ± 0.9 a2) of the chromatin chain. Conversion to the physical time can be made using τBD ≈ 50 ms.

Fig 2

doi: https://doi.org/10.1371/journal.pcbi.1006617.g002