Mechanistic insight into spontaneous transition from cellular alternans to arrhythmia—A simulation study
Fig 8
Role of anisotropy in transition from discordant alternans to re-entrant arrhythmias.
A. Snapshots of excitation waves in a homogeneous but anisotropic tissue with increased INa. PCL = 140 ms. B. Time series of APs recorded from 3 different registration sites, cell A, B and C as marked by black dots in the top-left panel. Red arrow: marking for the beginning of re-entry; Blue, black and red stars marked three consecutive stimulus pulses from the 10th stimulus.