Mechanistic insight into spontaneous transition from cellular alternans to arrhythmia—A simulation study
Fig 7
Role of inhomogeneity in transition from discordant alternans to re-entrant arrhythmias.
A. Snapshots of excitation waves in an inhomogeneous tissue with increased INa. PCL = 140 ms. B. Time series of APs recorded from 3 different registration sites, cell A, B and C as marked by black dots in the top-left panel. Red arrow: marking for the beginning of re-entry. Inhomogeneous tissue was simulated by assigning cells to dead cells randomly in the tissue.