Molecular characterization of breast and lung tumors by integration of multiple data types with functional sparse-factor analysis
Fig 9
Mutations and immune infiltration in lung cancer.
A: Mann-Whithney U statistic of the factor values between tumors with and without a mutation in a gene divided by the product of the number of tumors in each group. Only significant (p < 0.05) values are shown. B: Pearson correlation (ρ) between the factors and cell type fractions. Only significant correlations (p < 0.05, |ρ|> 0.2) are shown. C: Mutations in genes of the NFE2L2 pathway and STK11 (black: tumor is mutated in this gene).