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A Kirchhoff-Nernst-Planck framework for modeling large scale extracellular electrodiffusion surrounding morphologically detailed neurons

Fig 1

Model system of a 3-D cylinder of ECS containing a morphologically detailed neuron.

(A) The simulated domain is denoted by Ω, and the boundary is denoted by ∂Ω. Exchange of ions between the neuron and ECS was modeled as a set of point sources (marked by blue dots). Two measurement points were used to create time series in the Results-section. These are shown as the green and purple points. (B) Each point source was included as a sink/source of each ion species, as well as a capacitive current.

Fig 1

doi: https://doi.org/10.1371/journal.pcbi.1006510.g001