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meaRtools: An R package for the analysis of neuronal networks recorded on microelectrode arrays

Fig 4

Comparing features between treatments.

In panels A-C, treatment refers to genotype (heterozygous, +/- and homozygous, -/-). In panels D and E, treatment refers to drug treatment. A) Output tables are printed for every feature, holding average values (in this case, Spike Intensity per aEs) per well (rows) and for every recording analyzed (columns). B) Spike Intensity per aEs for two genotypes by DIV on a subset of five recordings. This graph corresponds to the full aggregated table of A). C) Same as B), but for a subset of eight recordings. D) Comparing the number of aEs for wells treated with a vehicle or one of two channel blocker treatments (0.1nM and 1nM) along a 27 DIV experiment. E) MFR for the same experiment as in D), showing differences in the effects of drug concentrations.

Fig 4

doi: https://doi.org/10.1371/journal.pcbi.1006506.g004