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Exploring the impact of inoculum dose on host immunity and morbidity to inform model-based vaccine design

Fig 9

Model for non-replicating vaccine.

Model parameters were set to d_V = 0.1, , h_V = 1E5, g_F = 1E3, F_max = 1E3, h_F = 100, g_B = 0.1, r_A = 1, d_A = 1E − 6, k_A = 1E − 6. Initial conditions are F = 1, B = 1, A = 0 and varying values for antigen load.

doi: https://doi.org/10.1371/journal.pcbi.1006505.g009