A benchmark driven guide to binding site comparison: An exhaustive evaluation using tailor-made data sets (ProSPECCTs)
Table 2
Summary of benchmark data sets used to analyze the individual strengths and weaknesses of different binding site comparison tools.
Similar and dissimilar binding site pairs are referred to as active and inactive pairs, respectively. The average overall G-factors were calculated with PROCHECK[66] and PROCHECK-NMR[67] to enable the quality comparison between all data sets including data set 2. Mean, standard deviation (stddev), minimum and maximum are given for all quality critieria.