A benchmark driven guide to binding site comparison: An exhaustive evaluation using tailor-made data sets (ProSPECCTs)
Fig 14
Binding site alignments for similar cavity pairs which most tools failed to identify.
(A) Alignment of human carbonic anhydrase II (PDB ID 1bn4, green) and cyclooxygenase-2 (PDB ID 6cox, purple) as obtained with IsoMIF. (B) The binding sites of synapsin (PDB ID 1aux, green) and PIM-1 kinase (PDB ID 3a99, purple) as aligned by SiteEngine. All illustrations were generated using UCSF Chimera[60].