A benchmark driven guide to binding site comparison: An exhaustive evaluation using tailor-made data sets (ProSPECCTs)
Fig 12
Results of a binding site feature analysis for the class A, B, and C pairs of Barelier et al.[64] and a sequence-culled subset of druggable binding sites. The relative frequencies of the binned properties are presented in light gray for class A structures, in dark gray for structures belonging to class B and C pairs, and in black for the sequence-culled sc-PDB[65] subset. The binding site features were calculated using DoGSite[73].