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In-silico dynamic analysis of cytotoxic drug administration to solid tumours: Effect of binding affinity and vessel permeability

Fig 1

Flow diagram of the coupled in-silico cancer modelling solver.

Diagram depicting all major compartments of the multiscale, multiphysics, in-silico cancer, angiogenesis and drug modelling framework, where the interaction between the biochemical and drug delivery module, the vascular network module and the solid and fluid mechanics solver modules is illustrated using arrows. Dotted arrows denote an implicit interplay between the corresponding compartments of the multiphysics in-silico framework.

Fig 1

doi: https://doi.org/10.1371/journal.pcbi.1006460.g001