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SIG-DB: Leveraging homomorphic encryption to securely interrogate privately held genomic databases

Fig 3

Intersection over union (IoU) scores for k-mer = {8, 16, 32} with random query sequence mutation rates from 0–100%.

K-mer = 8 showed best performance, with correct identification of sequence of interest up to mutation rates of 45%. The red circles indicate the largest mutation rate for each k-mer size that returned the correct result as the highest IoU value. The horizontal red line represents IoU = 0.1.

Fig 3

doi: https://doi.org/10.1371/journal.pcbi.1006454.g003