The physiological variability of channel density in hippocampal CA1 pyramidal cells and interneurons explored using a unified data-driven modeling workflow
Fig 8
Degeneracy in CA1 pyramidal neurons.
(A) Distribution of the normalized values obtained for the somatic KM, dendritic Na, Ih and Ra. (B) Radar plot with the values obtained for a subset of conductances. Parameters’ values were sorted for those obtained for Cagk (black line); Traces on the left are model traces from individuals #30, 46, 50 and 102 under a 0.4 nA somatic current injection. (C) Number of spikes elicited by a 0.4 nA current injection in each individual. Abbreviations as in Fig 4.