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The physiological variability of channel density in hippocampal CA1 pyramidal cells and interneurons explored using a unified data-driven modeling workflow

Fig 2

Experimental voltage traces used for the optimization pipeline.

(Top) Typical somatic traces obtained during a step current stimulation protocol (-0.4, 0.4 and 0.8 nA for 400 ms) from intracellular recordings performed using sharp electrodes on CA1 pyramidal cells (left) and interneurons (right) classified as continuous accommodating cells (cAC); (bottom) typical traces from interneurons classified as bursting accommodating, bAC, (left) and continuous non-accommodating, cNAC, (right) cells [18].

Fig 2

doi: https://doi.org/10.1371/journal.pcbi.1006423.g002