Unraveling the mechanism of the cadherin-catenin-actin catch bond
Fig 6
The effects of mutating the angular barrier height H from the original value of 25 kBT down to zero, in increments of 5 kBT, leaving all other model parameters fixed at their Table 1 values: A) the mean bond lifetime τ(F); B) the mean lifetime τL(F) of remaining in the large angle conformational state, α > αc, measured from the initial time of entry into the state; C) the survival probability ΣF(t) at F = 7 pN.