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A comprehensive ensemble model for comparing the allosteric effect of ordered and disordered proteins

Fig 10

The properties under Ising-like interface interactions.

(a) Distribution of lnα when the Ising-like interface interactions of the Allosteric Ising Model (AIM) were introduced to combine with the MWC and EAM models. The variation range of Ising interface energy is ΔGmax = 3 RT. (b) The capacity of three pathways in the comprehensive ensemble model when the interface interactions are Ising-like. The variation range (ΔGmax) for free-energy parameters is 8 kcal/mol.

Fig 10

doi: https://doi.org/10.1371/journal.pcbi.1006393.g010