A comprehensive ensemble model for comparing the allosteric effect of ordered and disordered proteins
Fig 9
Analysis results with other measures of allostery.
(a) Distribution of lnα where α is the thermodynamic allosteric efficacy defined in Eq (13), as well as the capacity of three pathways. (b) The average weights of pathways as functions of lnα. (c) The average thermodynamic coupling function [ΔΔFi, as defined in Eq (15), and in a unit of RT] at some states as functions of lnα. (d) The average normalized allosteric coupling [AC, as defined in Eq (16)] of some states as functions of lnα. The variation range (ΔGmax) for free-energy parameters is 8 kcal/mol.