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A comprehensive ensemble model for comparing the allosteric effect of ordered and disordered proteins

Fig 7

The influence of the variation range (ΔGmax, in a unit of kcal/mol) for free-energy parameters (ΔGR1, ΔGR2, ΔGRT1, ΔGRT2, Δgint,R, Δgint,T) of the comprehensive ensemble model with the A-R binding mode.

(a) The possibilities for three pathways [calculated with Eq (12)] obtained at different [–ΔGmax, +ΔGmax] range. (b) The probabilities of CR > 0.171 as a function of ΔGmax.

Fig 7

doi: https://doi.org/10.1371/journal.pcbi.1006393.g007