A comprehensive ensemble model for comparing the allosteric effect of ordered and disordered proteins
Fig 3
Three allosteric subsystems/pathways in the comprehensive ensemble model.
The arrows indicate the population shifts caused by ligand binding which are capable of affecting the substrate binding (see text for details). The A-R binding mode is assumed here. The contribution ratios of pathways to the allostery of the comprehensive system are given in Eqs (4–7).