Norepinephrine stimulates glycogenolysis in astrocytes to fuel neurons with lactate
Fig 5
Glycogen and cellular energy status.
A) mobilization of glycogen in response to NE-triggered cAMP at each of 4 cyclase amplification coefficients (cyclase coef. in panels). B) Indicators of cellular energy status: astrocytic, cytosolic NAD+/NADH ratio (oxidative state) as well as energy charge ((ATP + 0.5ADP)/(ATP+ADP+AMP)) in response to cAMP. NE duration indicated by gray shaded areas.