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Norepinephrine stimulates glycogenolysis in astrocytes to fuel neurons with lactate

Fig 1

Visualization of glycogen granules in a 3D reconstructed astrocyte.

A) Rendering of one astrocytic process (grey), in semi-transparency to highlight the presence within its cytosol of the glycogen granules. B) Top and bottom panels, rendering of two reconstructed astrocytic processes (green, adult, red, aged), semi-transparent to show the intracellular content of glycogen granules (grey). Whisker plot of the density of glycogen granules per astrocytic process in adult (4 months old 442.3 ± 112.2 granules / μ3, n = 3) and aged (24 months old; 526.3 ±98.6 granules / μ3, n = 3).

Fig 1

doi: https://doi.org/10.1371/journal.pcbi.1006392.g001