Network-level allosteric effects are elucidated by detailing how ligand-binding events modulate utilization of catalytic potentials
Fig 2
Catalytic potential plots for the base model (glycolysis, the RL Shunt, and hemoglobin) plus an enzyme module for (A) PFK, (B) HEX, and (C) PYK individually.
The inset in panel (C) shows the concentration profile of FDP (see Fig D in S1 File for the detailed concentration profile).