A model for hydrophobic protrusions on peripheral membrane proteins
Fig 10
Large aliphatic and aromatic side chains are over-represented on protrusion on peripheral proteins.
Panel A shows the weighted fractions (Eq 4) of hydrophobic amino acids on protrusions from peripheral proteins (blue) and from proteins in the reference set (red, ‘Non-binding surfaces’). In panel B, the contrast between the two sets is quantified by the odds ratio (Eq 10), so that positive values reflect higher frequencies in the set of peripheral proteins than in the reference set. More precisely the vertical axis denote with aa representing each of the standard amino acids. Error bars are 95% confidence intervals.