A model for hydrophobic protrusions on peripheral membrane proteins
Fig 2
Hydrophobes are more common on protruding positions in peripheral proteins than in the reference sets.
The plots show frequencies of hydrophobes on surface amino acids, both on protrusions (A, C, E, G) and among all solvent exposed amino acids (B, D, F, H) for peripheral proteins (blue) and the reference datasets (red). The horizontal axes show the mean fraction (Eq 1) of protrusions or solvent exposed amino-acids that are hydrophobic. The vertical axis shows the fraction of protein families for each set. Plots A-D show the comparison between the data sets ‘Peripheral’ and ‘Non-binding surfaces’, and E-H the comparison between ‘Peripheral-P’ and ‘Reference Proteins’.