Quantitative cell-based model predicts mechanical stress response of growing tumor spheroids over various growth conditions and cell lines
Fig 10
(A) Time evolution of the radius of the thin capsule, shown for the experimental data and the simulation using Model I, with parameter variation on the individual cell compressibility (K(V) means strain hardening). (B) Time evolution of the simulated cell density. The dashed horizontal line indicates the experimentally observed cell density at 48h. (C) Pressure in the capsule versus time.