Evaluating reproducibility of AI algorithms in digital pathology with DAPPER
Fig 2
The tissue detection pipeline.
The identification of the tissue bounding box is performed on the WSI thumbnail in three steps: a) Binarization of the grayscale image by applying Otsu’s thresholding; b) Binary dilation and filling of the holes; c) Selection of the biggest connected region as tissue region and computation of the vertex of the containing rectangle.