FusionPathway: Prediction of pathways and therapeutic targets associated with gene fusions in cancer
Fig 3
Prediction evaluation of three known BCR-ABL1 variants (p185, p210, and p230).
(A) Number of predicted protein-protein interaction partners of the three BCR-ABL1 variants. (B) Correlations of pathway prediction of the three BCR-ABL1 variants. GSEA association scores of categorized pathways in the MSigDB database (category C2) were used for calculating spearman correlations. (C) Oncogenic impact evaluation of the three BCR-ABL1 variants using genes categorized in the KEGG cancer pathway.