Proteome-scale relationships between local amino acid composition and protein fates and functions
Fig 3
Maximum local amino acid composition is associated with residue-specific differences in protein abundance.
For each amino acid, protein abundance values corresponding to proteins partitioned into a given window size and percent composition bin were compared to values for all proteins of length ≥ the corresponding window size that were excluded from the bin. For this figure and related subsequent figures, red and blue points indicate bins for which the distribution of protein abundance values differ significantly (Bonferroni-corrected p ≤ 0.05) from those of excluded proteins: red points indicate bins with a lower median value relative to that of excluded proteins, whereas blue points indicate bins with a higher relative median value. Grey points indicate comparisons lacking statistical significance. Individual points are scaled within each subplot to reflect the sample sizes of proteins contained within each bin.