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Reversing allosteric communication: From detecting allosteric sites to inducing and tuning targeted allosteric response

Fig 7

Receiver operating characteristic (ROC) curves.

(A) High predictive power can be achieved for most allosteric proteins with distant functional and allosteric sites. (B) Allosteric sites for which low predictive powers are obtained. (C) A histogram of the area under the ROC curves (AUCs) for the detection of allosteric sites in proteins from the additional benchmark set of 41 proteins.

Fig 7

doi: https://doi.org/10.1371/journal.pcbi.1006228.g007