Quantitative theory of deep brain stimulation of the subthalamic nucleus for the suppression of pathological rhythms in Parkinson’s disease
Fig 5
Peak power of STN firing rate ϕζ during a 40 s simulation within the frequency band f = 20–30 Hz using a time window t = 20–40 s.
(a) Dependence of peak f = 20–30 Hz power on DBS pulse frequency with νζx = −1.2 mVs and mVs. (b) Change in peak f = 20–30 Hz power by a direct constant perturbation to the soma potential (dashed) and by an indirect perturbation resulting from an oscillating DBS input (solid), as described in Fig 2. For each point Vζ = Vζ + ΔV,
, and
.