Network supporting contextual fear learning after dorsal hippocampal damage has increased dependence on retrosplenial cortex
Fig 3
dHPC lesion does not impair CFC learning and memory.
(A) Schematic diagram showing the distribution of the lesions in the dHPC group. (B) Mean (black line) and bootstrapped 95% CI of the Total Freezing Time during the five min context fear memory test of dHPC (N = 12), SHAM (N = 12) and Imm (N = 8) groups. The open circles show data distribution in each group. (C) Cumulative distribution of the sample as a function of Freezing Time showing the sample distributions. The “*” shows a significant difference from Imm at level of p<0.05. (D) Mean (black line) and Bootstrapped 95% CI of the mean (boxplots) of the pCREB-positive nuclei density in each region and each group. The black dots show the data point distributions.