miRAW: A deep learning-based approach to predict microRNA targets by analyzing whole microRNA transcripts
Fig 6
Composition of site types identified by the different CSSMs implemented in miRAW.
(a) Average number of miRNA binding sites (MBSs) identified by the different CSSMs in a miRNA:mRNA pair. Blue color refer to MBS following a canonical structure, green refer to non-canonical sites; darker colors correspond to positive sites predicted in experimentally verified functional miRNA:mRNA pairs (true positives), lighter colors refer to positive sites identified in non-functional pairs (false positives). (b) Proportion of canonical, non-canonical, true positive and false negative sites identified by each of the candidate site selection methods. Figures illustrate that miRAW-Pita and miRAW-TS CSSMs are strongly biased towards detection of canonical sites whereas miRAW specific CSSMs detect a higher proportion of non-canonical sites.