On the role of sparseness in the evolution of modularity in gene regulatory networks
Fig 4
Selection for two GAPs produces a greater increase in modularity in sparser networks.
The selection regimes are the same as in Fig 3. In a first stage, selection favoured networks that produced target GAP I. In a second stage, networks with highest fitness were those that produced GAPs I and II in cells with different initial system states (Fig 3A). The score refers to a partition P that assigns the first five genes to one set and the rest of the genes to another. The number of expected interactions is modulated through γ, the relative propensity to acquire interactions.