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Firing-rate based network modeling of the dLGN circuit: Effects of cortical feedback on spatiotemporal response properties of relay cells

Fig 13

Delayed inhibitory feedback sharpens the temporal frequency tuning of relay cells, while delayed excitatory feedback blunts the temporal frequency tuning of relay cells.

Effect of cortical feedback on temporal frequency tuning of relay cells are shown for different values of thalamocortical delay. Panel A: inhibitory feedback only. Panel B: excitatory feedback only. Panel C, left: delayed inhibition, i.e., rapid excitatory feedback combined with long-delay inhibitory feedback ( ms, ms). Panel C, center: synchronized feedback, i.e., excitatory and inhibitory feedback arrive simultaneously ( ms). Panel C, right: delayed excitation, i.e., long-delay excitatory feedback combined with rapid inhibitory feedback ( ms, ms). Full-field grating is used as stimulus (|kg| ≈ 1deg−1) and default values from Table 1 is used for fixed parameters.

Fig 13

doi: https://doi.org/10.1371/journal.pcbi.1006156.g013