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Firing-rate based network modeling of the dLGN circuit: Effects of cortical feedback on spatiotemporal response properties of relay cells

Fig 7

Mixed feedback may enhance both excitatory response to stimuli within the receptive-field center (unlike inhibitory feedback alone), and suppressive effects of stimuli in the surround (unlike excitatory feedback alone).

Top row: predicted area-response curves of relay cells for different arrangements of cortical feedback using static spot stimuli. Bottom row: optimal size and suppression index (αs) are shown as a function of cortical feedback weight for different feedback configurations. These are extracted from the size tuning curve using static spot (solid lines, top row) and patch grating (dashed lines, |kg| ≈ 1/deg) as stimulus (bottom left figure). The values on the x-axis represent factors multiplied with the default values for and listed in Table 1. Default values for fixed parameters are also listed in this table.

Fig 7

doi: https://doi.org/10.1371/journal.pcbi.1006156.g007