A computational model of epithelial solute and water transport along a human nephron
Fig 2
Total delivery of key solutes (A–G) and fluid (H) to the beginning of individual nephron segments, given per kidney.
Model predicts that the majority of key solutes and volume are reabsorbed by the proximal tubule (PT). The distal tubular segments are responsible for the secretion of K+ and acid species. DL, descending limb; mTAL, medullary thick ascending limb; DCT, distal convoluted tubule; CNT, connecting duct; CCD, cortical collecting duct. TA, titratable acid. Insets reproduce distal segment and urine values.