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A loop-counting method for covariate-corrected low-rank biclustering of gene-expression and genome-wide association study data

Fig 9

Continuous–covariate-distribution from Example-B as the loop-counting algorithm proceeds.

On top we show several scatterplots, sampling from different iterations as our algorithm proceeds. Each scatterplot illustrates the 2-dimensional distribution of covariate-components across the remaining case-patients at that point in the iteration. The horizontal and vertical lines in each subplot indicate the medians of the components of the covariate-distribution. Below we show the same data again, except in contour form (note colorbar). Note that the covariate-distribution remains relatively well-distributed as the algorithm proceeds.

Fig 9

doi: https://doi.org/10.1371/journal.pcbi.1006105.g009