Optimal dynamic control approach in a multi-objective therapeutic scenario: Application to drug delivery in the treatment of prostate cancer
Fig 1
Typical testosterone profile after administration of triptorelin.
TSTmax refers to the maximal testosterone concentrations, tcast indicates the time where testosterone levels fall below 0.5ng/ml (castration limit of prostate cancer patients, marked with an horizontal dashed line in the figure) and teffect indicates the castration period of the patients.