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Activation gating in HCN2 channels

Fig 3

Effect of cAMP on the time-dependent population of states.

The time courses were computed with model 1_n (no cAMP) or 1_a (10 μM cAMP). (a,b) Full activation and deactivation without and with cAMP. (c,d) Moderate voltage-dependent activation and deactivation without and with cAMP.

doi: https://doi.org/10.1371/journal.pcbi.1006045.g003