Particle-based simulations of polarity establishment reveal stochastic promotion of Turing pattern formation
Fig 4
Simulations of polarity establishment within the Turing unstable regime.
Snapshots of total Cdc42-GTP (both Cdc42-GTP and Bem1-GEF-Cdc42-GTP). Top: Particle-based simulations. Red dots represent individual molecules. Bottom: Reaction-diffusion partial differential equation simulations. (A) Individual molecules in particle-based simulations, and individual pixels in 100x100 grid RDE simulations. Scale bar, 0.5 μm. (B) To compare the polarity patches, 2D histograms of the final polarized states were computed, where both distributions were binned on coarsened 20x20 grids.