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Metabolic enzyme cost explains variable trade-offs between microbial growth rate and yield

Table 1

Focal EFMs representing different growth strategies.

Metabolic fluxes are given in carbon moles (or O2 moles) per carbon moles of glucose uptake. Growth rates are given for reference conditions [glucose] = 100 mM, and [O2] = 0.21 mM. For more details, see Table 10 in S1 Text. Abbreviations: * max-gr: maximum growth rate; max-yield: maximum yield; pareto: a Pareto optimal EFM with higher growth rate than max-yield, and higher yield than max-gr; ana-lac: anaerobic lactate fermentation; aero-ace: aerobic acetate fermentation; exp: experimentally measured flux distribution.

Table 1

doi: https://doi.org/10.1371/journal.pcbi.1006010.t001