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Same but not alike: Structure, flexibility and energetics of domains in multi-domain proteins are influenced by the presence of other domains

Fig 9

Cross-correlation matrices of the functional residues.

(A) Phosphoribosylanthranilate isomerase, (B) cyclophilin, (C) sialidase and, (D) hexokinase-1. The first row represents the matrices for multi-domain proteins, the second row represents the matrices for single-domain and, the last row represents the chimeras. The X-axis and the Y-axis represent the residue number of the functional residues. The color bar represents the cross-correlation values.

Fig 9

doi: https://doi.org/10.1371/journal.pcbi.1006008.g009