Same but not alike: Structure, flexibility and energetics of domains in multi-domain proteins are influenced by the presence of other domains
Fig 1
An example of a domain pair used in the analysis.
Rat DNA polymerase β consists of three domains (represented in red, blue and green). The protein has been crystallized (A) as full length, with all the three domains (PDB id. 1BPD) and (B) with two C-terminal domains (PDB id. 1RPL). For all the analyses, various properties of the common domains between the members of the pair namely the DNA polymerase β domain (colored blue) and DNA polymerase β catalytic domain (colored green) are compared.