Multiscale modeling of layer formation in epidermis
Fig 2
(A) A schematic diagram shows the roles of Ovol proteins in epidermal development and differentiation. Red dashed lines represent the potential regulation exerted by Ovol on components of the cell lineage model. (B) Immunofluorescence images showing a mild decrease in the size of the K14-positive compartment in Ovol2-overexpressing epidermis at E18.5. Scale bar represents 50 μm. (C) GSEA of microarray data from E17.5 embryos (2 biological replicates per genotype) with Normalized Enrichment Score (NES), p-value (P), and False Discovery Rate (FDR).