Trade-off between synergy and efficacy in combinations of HIV-1 latency-reversing agents
Fig 1
Schematic of the HIV-1 latency circuit.
The events associated with HIV-1 transcription and translation that govern the latency of an HIV-1 infected cell are depicted as a set of reactions (see Eqs (1)–(18) in Methods). The entities involved in the reactions are described in Results and the rate constants of the reactions are in Table 1.