Hub connectivity, neuronal diversity, and gene expression in the Caenorhabditis elegans connectome
Fig 8
Increased CGE of hub neurons is not driven by modularity, neuronal birth time, or cell lineage distance.
(A) Distributions of CGE, rϕ, for intra-modular rich (red) non-rich (blue) connections, shown as violin plots with the median shown as a horizontal bar (Wilcoxon rank sum test, p = 6.9 × 10−17). (B) Distributions of CGE, rϕ, for inter-modular rich (red) and non-rich (blue) connections, shown as violin plots with the median shown as a horizontal bar (Wilcoxon rank sum test, p = 1.6 × 10−5). (C) Distributions of lineage distance between rich links (red) and non-rich links (blue), plotted as histograms due to a discrete nature of this measure (Wilcoxon rank sum test, p = 0.079). (D) Distributions of CGE, rϕ, between early born hubs (rich links, red) and nonhubs (non-rich links, blue) shown as violin plots with the median shown as a horizontal bar (Wilcoxon rank sum test, p = 3.9 × 10−22). (E) Distributions of CGE between hub command interneurons (red) and hub non-command interneurons (blue) shown as violin plots with the median shown as a horizontal bar (Wilcoxon rank sum test, p = 3.3 × 10−8). * represents statistically significant differences.