Hub connectivity, neuronal diversity, and gene expression in the Caenorhabditis elegans connectome
Fig 4
Dependence of correlated gene expression, rϕ, on spatial separation between pairs of neurons.
Correlated gene expression, rϕ (excluding bilateral homologous pairs of neurons), is shown as a function of the pairwise separation distance between pairs of neurons (shown as the mean (solid) ± standard deviation (dotted) in seven equiprobable distance bins, with extent shown as horizontal bars), for (A) all pairs of neurons in the head, (B) all pairs of neurons in the tail, and (C) all other pairs (labeled). Scatters for all neuron pairs are added in (A) and (B). An exponential relationship, f(x) = A exp(−λx) + B, is fitted in (A) and (B). The weak decreasing trend in rϕ with distance, is primarily driven by a small subset of nearby neurons with high rϕ, and may therefore represent a more specific relationship between particular neurons, rather than a general, bulk spatial relationship observed in macroscopic mammalian brains [38, 42].