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Systems-level computational modeling demonstrates fuel selection switching in high capacity running and low capacity running rats

Fig 8

Histograms of HCR and LCR enzyme activity ratios (XHCR/XLCR) from multiple parameter sets.

A 103 parameter sets, each composed of 86 enzyme activities, individually fitted to HCR and LCR data were used to obtain a multitude of enzyme activity ratios (XHCR/XLCR). All combinations of each of the 103 parameter sets for HCR and LCR were used yielding 106 ratios for each of the 86 enzyme activities. Each histogram panel in the figure represents one of the 86 enzyme activity ratios and are annotated per the shortened enzyme identifier defined in S1 Table. In each histogram panel, the y-axis represents the frequency of ratio (XHCR/XLCR) occurrence and the x-axis represents the value of the ratio.

Fig 8

doi: https://doi.org/10.1371/journal.pcbi.1005982.g008